SIN3A antibody (AA 1-50)

Catalog No. ABIN7448796

The Rabbit Polyclonal anti-SIN3A antibody (ABIN7448796) specifically detects SIN3A in IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for SIN3A antibody (AA 1-50) (ABIN7448796)

Target: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIN3A antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-SIN3A Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-Sin3A IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine,Dog,Horse,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Chinese hamster,Northern white-cheeked gibbon,African elephant,Crab-eating macaque,Thirteen-lined ground squirrel,Tasmanian devil,Little brown bat,Small-eared galago,Gray short-tailed opossum,Ferret,White-tufted-ear marmoset

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SIN3A

Target: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Alternative Name: Sin3A

Background: Background: Sin3A is a part of a histone deacetylase co-repressor complex that functions to stabilize complex members and regulate gene expression through deacetylation of histones. Sin3A acts as a scaffold for a core complex which contains HDAC1, HDAC2, RbAp46, RbAp48, SAP30, RBP1 and p33INHib. Sin3A also associates with the Mad/Max complex to mediate transcriptional repression.

Gene ID: 25942

NCBI Accession: NP_056292

UniProt: Q96ST3

Pathways: Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha