IRS2 antibody (AA 1288-1338)

Catalog No. ABIN7448980

This Rabbit Polyclonal antibody specifically detects IRS2 in IHC and IF (p). It exhibits reactivity toward Human.

Quick Overview for IRS2 antibody (AA 1288-1338) (ABIN7448980)

Target: IRS2 (Insulin Receptor Substrate 2 (IRS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRS2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-IRS2 Antibody

Binding Specificity: AA 1288-1338

Purpose: Rabbit anti-IRS2 IHC Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1288 and 1338

Isotype: IgG

Application Details

Application Notes:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for IRS2

Target: IRS2 (Insulin Receptor Substrate 2 (IRS2))

Alternative Name: IRS2

Background: Background: IRS2 (insulin receptor substrate 2) functions as a cytoplasmic link and transducer of insulin receptor (IR) and insulin-like growth factor receptor (IGFR) signaling. As the name implies, IRS2 is a substrate of IR and IGFR tyrosine kinase activity activated by insulin and IGF binding.

Gene ID: 8660

NCBI Accession: NP_003740

UniProt: Q9Y4H2

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process