1:100 - 1:1,000. ABIN7449207 has been shown to react with purified recombinant ADAM-TS13. It has not been tested for reactivity with ADAM-TS13 from native sources, and the antibody is not warranted to have such activity.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Expiry Date
12 months
Target
ADAMTS13
(ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13))
Alternative Name
ADAMTS13
Background
Background: ADAMTS13 is part of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family that is responsible for cleaving von Willebrand Factor (vWF). ADAMTS13 is synthesized in the liver and secreted to the plasma. A deficiency of the ADAMTS13 protease activity results in unusually larger multimers of vWF and is associated with thrombotic thrombocytopenic purpura.