Syntaxin 17 antibody (AA 150-200)

Catalog No. ABIN7449258

This anti-Syntaxin 17 antibody is a Rabbit Polyclonal antibody detecting Syntaxin 17 in WB. Suitable for Human.

Quick Overview for Syntaxin 17 antibody (AA 150-200) (ABIN7449258)

Target: Syntaxin 17 (STX17)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syntaxin 17 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Syntaxin 17 Antibody

Binding Specificity: AA 150-200

Purpose: Rabbit anti-STX17 Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: Between AA 150 and 200

Isotype: IgG

Application Details

Application Notes: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Syntaxin 17

Target: Syntaxin 17 (STX17)

Alternative Name: STX17

Background: Background: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane (PubMed:23217709, PubMed:25686604). May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi (PubMed:21545355) [taken from the Universal Protein Resource (UniProt) P56962].

Gene ID: 55014

UniProt: P56962

Pathways: Synaptic Vesicle Exocytosis