RPS6KB1 antibody (C-Term)

Catalog No. ABIN7449265

This Rabbit Polyclonal antibody specifically detects RPS6KB1 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for RPS6KB1 antibody (C-Term) (ABIN7449265)

Target: RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS6KB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RPS6KB1 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-p70S6K Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine,Rabbit

Purification: Affinity Purified

Immunogen: between AA 475 and C-term

Isotype: IgG

Application Details

Application Notes: 1:2,500 - 1:20,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RPS6KB1

Target: RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))

Alternative Name: p70S6K

Background: Background: 70 kDa ribosomal protein S6 kinase I (p70S6K) encodes a member of the ribosomal S6 kinase family that phosphorylates the 40 S ribosomal subunit protein S6 and eukaryotic translation initiation factor 4B (eIF4B). p70S6 functions in the PI3K and mTOR pathway to induce protein synthesis and cell growth and proliferation in response to growth factors. S6K2 is an isoform of p70S6K.

Gene ID: 6198

NCBI Accession: NP_003152

UniProt: P23443

Pathways: PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Regulation of Cell Size, Skeletal Muscle Fiber Development, Feeding Behaviour, G-protein mediated Events, Smooth Muscle Cell Migration, Interaction of EGFR with phospholipase C-gamma, Warburg Effect