Recombinant CD80 antibody (AA 35-246)

Catalog No. ABIN7449415

This Rabbit Monoclonal antibody specifically detects CD80 in FACS, WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant CD80 antibody (AA 35-246) (ABIN7449415)

Target: CD80

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD80 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC)

Clone: BLR206K

Product Details anti-CD80 Antibody

Binding Specificity: AA 35-246

Purpose: Rabbit anti-CD80 Recombinant Monoclonal Antibody [BLR206K]

Immunogen: residues 35-246 (ECD)

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 to 1:500. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections. Extended primary antibody incubation (16 hours - 24 hours) is recommended.

WB: 01:01,00

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CD80

Target: CD80

Alternative Name: CD80

Background: Background: CD80 is a membrane receptor involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. [taken from the Universal Protein Resource (UniProt) P33681].

Gene ID: 941

NCBI Accession: NP_005182

UniProt: P33681

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints