BLM antibody (AA 1-50)

Catalog No. ABIN7449605

The Rabbit Polyclonal anti-BLM antibody has been validated for IP. It is suitable to detect BLM in samples from Mouse.

Quick Overview for BLM antibody (AA 1-50) (ABIN7449605)

Target: BLM (Bloom Syndrome RecQ Like Helicase (BLM))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BLM antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-BLM Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-BLM Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 1 - 4 μg/mg lysate

WB: Not recommended. Use rabbit anti-BLM antibody ABIN7450035 for WB of mouse BLM.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BLM

Target: BLM (Bloom Syndrome RecQ Like Helicase (BLM))

Alternative Name: BLM

Background: Background: Bloom syndrome protein (BLM) is a RecQ DNA-helicase that plays a role in DNA replication and repair. Mutations and inactivation of BLM result in human syndromes characterized by dwarfism, infertility, erythema, learning disabilities, immune deficiency and predisposition to cancer. BLM has been shown to associate with the BRCA1-associated genome surveillance complex (BASC) which contains BRCA1, MSH2, MSH6, MLH1, ATM, PMS2 and the RAD50-MRE11-NBS1 protein complex.

Gene ID: 12144

NCBI Accession: NP_031576

UniProt: O88700

Pathways: DNA Damage Repair