FANCB antibody (AA 820-859)

Catalog No. ABIN7449654

The Rabbit Polyclonal anti-FANCB antibody (ABIN7449654) specifically detects FANCB in IP. The antibody is reactive with Human samples.

Quick Overview for FANCB antibody (AA 820-859) (ABIN7449654)

Target: FANCB (Fanconi Anemia, Complementation Group B (FANCB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCB antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-FANCB Antibody

Binding Specificity: AA 820-859

Purpose: Rabbit anti-FANCB Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 820 and 859

Isotype: IgG

Application Details

Application Notes:

IP: 10 μg/mg lysate

WB: Not recommended.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FANCB

Target: FANCB (Fanconi Anemia, Complementation Group B (FANCB))

Alternative Name: FANCB

Background: Background: FANCB (Fanconi anemia complementation group B) is part of a DNA repair network which involves BRCA1 and BRCA2 and required for the ubiquitination of FANCD2. The FANCB gene is one of 13 complementation groups that include FANCA, FANCB, FANCC, FANCD1/BRCA2, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ/BRIP1, FANCL, FANCM, and FANCN/PALB2. The FANC members are not homologous proteins but are related by their assembly into a common nuclear complex. Defects in FANCB are the cause of Fanconi pancytopenia type 2, Fanconi anemia, and X-linked VACTERL.

Gene ID: 2187

NCBI Accession: NP_001018123

UniProt: Q8NB91

Pathways: DNA Damage Repair