MDM4-binding Protein antibody (AA 125-175)

Catalog No. ABIN7449748

This Rabbit Polyclonal antibody specifically detects MDM4-binding Protein in WB and IP. It exhibits reactivity toward Human.

Quick Overview for MDM4-binding Protein antibody (AA 125-175) (ABIN7449748)

Target: MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MDM4-binding Protein antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-MDM4-binding Protein Antibody

Binding Specificity: AA 125-175

Purpose: Rabbit anti-HdmX/MDM4 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 125 and 175

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MDM4-binding Protein

Target: MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

Alternative Name: HdmX/MDM4

Background: Background: HdmX/MDM4 is a RING-finger domain containing protein that interacts with p53. HdmX/MDM4 may influence p53 stability through an interaction with the structurally similar MDM2, an ubiquitin-ligase that targets p53 for proteasomal degradation. HdmX/MDM4 may influence p53 by directly attenuating p53 transcriptional activity.

Gene ID: 4194

NCBI Accession: NP_002384

UniProt: O15151

Pathways: Cell Division Cycle