HIP1 antibody (AA 987-1037)

Catalog No. ABIN7449887

The Rabbit Polyclonal anti-HIP1 antibody has been validated for WB and IP. It is suitable to detect HIP1 in samples from Human.

Quick Overview for HIP1 antibody (AA 987-1037) (ABIN7449887)

Target: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-HIP1 Antibody

Binding Specificity: AA 987-1037

Purpose: Rabbit anti-HIP1/Huntingtin-interacting Protein 1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 987 and 1037

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for HIP1

Target: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Alternative Name: HIP1/Huntingtin-interacting Protein 1

Background: Background: The product of gene HIP1, Huntingtin-interacting protein 1, is a membrane-associated protein that functions in clathrin-mediated endocytosis and protein trafficking within the cell. The encoded protein, as its name would imply, binds to huntingtin protein in the brain and this interaction is lost in Huntington's disease [taken from NCBI Entrez Gene (Gene ID: 3092)].

Gene ID: 3092

UniProt: O00291

Pathways: Positive Regulation of Endopeptidase Activity