SREBF chaperone antibody (AA 450-500)

Catalog No. ABIN7449916

This Rabbit Polyclonal antibody specifically detects SREBF chaperone in WB and IP. It exhibits reactivity toward Human.

Quick Overview for SREBF chaperone antibody (AA 450-500) (ABIN7449916)

Target: SREBF chaperone (SCAP)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SREBF chaperone antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-SREBF chaperone Antibody

Binding Specificity: AA 450-500

Purpose: Rabbit anti-SCAP Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 450 and 500

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SREBF chaperone

Target: SREBF chaperone (SCAP)

Alternative Name: SCAP

Background: Background: Sterol regulatory element-binding protein cleavage-activating protein (SCAP) is a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, SCAP binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis [taken from NCBI Entrez Gene (Gene ID: 22937)].

Gene ID: 22937

NCBI Accession: NP_036367

UniProt: Q12770

Pathways: SARS-CoV-2 Protein Interactome