BAG2 antibody (AA 1-50)
Quick Overview for BAG2 antibody (AA 1-50) (ABIN7450017)
Target
See all BAG2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-50
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Purpose
- Rabbit anti-BAG2 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- Between AA 1 and 50
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Isotype
- IgG
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Application Notes
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- BAG2 (BCL2-Associated Athanogene 2 (BAG2))
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Alternative Name
- BAG2
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Background
- Background: BAG (Bcl-2-associated athanogene) proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner [taken from NCBI Entrez Gene (Gene ID: 9532)].
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Gene ID
- 9532
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UniProt
- O95816
Target
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