BCL10 antibody (AA 183-233)

Catalog No. ABIN7450023

The Rabbit Polyclonal anti-BCL10 antibody (ABIN7450023) specifically detects BCL10 in WB and IP. The antibody is reactive with Human samples.

Quick Overview for BCL10 antibody (AA 183-233) (ABIN7450023)

Target: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL10 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-BCL10 Antibody

Binding Specificity: AA 183-233

Purpose: Rabbit anti-Bcl10 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 183 and 233

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BCL10

Target: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Alternative Name: Bcl10

Background: Background: B-cell lymphoma/leukemia 10 (Bcl10) promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. Bcl10 may be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Bcl10 Is a substrate for MALT1 [taken from the Universal Protein Resource (UniProt) O95999].

Gene ID: 8915

NCBI Accession: NP_003912

UniProt: O95999

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins