CASC5 antibody (AA 300-350)

Catalog No. ABIN7450069

This Rabbit Polyclonal antibody specifically detects CASC5 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for CASC5 antibody (AA 300-350) (ABIN7450069)

Target: CASC5 (Cancer Susceptibility Candidate 5 (CASC5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASC5 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-CASC5 Antibody

Binding Specificity: AA 300-350

Purpose: Rabbit anti-CASC5 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 300 and 350

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CASC5

Target: CASC5 (Cancer Susceptibility Candidate 5 (CASC5))

Alternative Name: CASC5

Background: Background: Cancer susceptibility candidate gene 5 protein (CASC5) is predominantly expressed in testis and widely expressed in various human tumor cell lines and primary tumors from various tissues and organs. CASC5 is most frequently expressed in lung cancer and has been identified as a fusion-partner of the mixed lineage leukemia (MLL) gene, a gene often activated by chromosomal translocation in leukemias. CASC5 has also been identified as a component of the Mis12 kinetochore complex that is required for proper chromosome segregation.

Gene ID: 57082

NCBI Accession: NP_733468

UniProt: Q8NG31

Pathways: Maintenance of Protein Location, Autophagy