DICER1 antibody (AA 600-650)

Catalog No. ABIN7450171

This Rabbit Polyclonal antibody specifically detects DICER1 in WB and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for DICER1 antibody (AA 600-650) (ABIN7450171)

Target: DICER1 (Dicer 1, Ribonuclease Type III (DICER1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DICER1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-DICER1 Antibody

Binding Specificity: AA 600-650

Purpose: Rabbit anti-Dicer Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 600 and 650

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DICER1

Target: DICER1 (Dicer 1, Ribonuclease Type III (DICER1))

Alternative Name: Dicer

Background: Background: Dicer is one of three human RNase III enzymes (Drosha, Dicer, and Argonaute) that plays a diverse role in the processing and maturation of RNA. Dicer is involved in processing pre-cursor mRNAs into both microRNAs (miRNAs) and short interfering RNAs (siRNAs) for the gene-silencing pathways of RNA interference (RNAi). Dicer interacts with Argonaute 2 (Ago2) and TRBP (TAR RNA-binding protein).

Gene ID: 23405

NCBI Accession: NP_085124

UniProt: Q9UPY3

Pathways: Regulatory RNA Pathways, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization