FAT1 antibody (AA 4450-4500)

Catalog No. ABIN7450240

This Rabbit Polyclonal antibody specifically detects FAT1 in WB and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for FAT1 antibody (AA 4450-4500) (ABIN7450240)

Target: FAT1 (FAT Tumor Suppressor Homolog 1 (FAT1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-FAT1 Antibody

Binding Specificity: AA 4450-4500

Purpose: Rabbit anti-FAT1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 4450 and 4500

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FAT1

Target: FAT1 (FAT Tumor Suppressor Homolog 1 (FAT1))

Alternative Name: FAT1

Background: Background: Protocadherin Fat 1 is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. FAT1 is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, FAT1 has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. FAT1 is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communicatio [taken from NCBI Entrez Gene (Gene ID: 2195)].

Gene ID: 2195

NCBI Accession: NP_005236

UniProt: Q14517