HRS (HRS) (C-Term) antibody

Catalog No. ABIN7450342

This Rabbit Polyclonal antibody specifically detects in WB and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for HRS (HRS) (C-Term) antibody (ABIN7450342)

Target: HRS

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details

Binding Specificity: C-Term

Purpose: Rabbit anti-HRS Antibody, Affinity Purified

Predicted Reactivity: Bovine

Purification: Affinity Purified

Immunogen: between AA 727 and C-term

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details

Target: HRS

Alternative Name: HRS

Background: Background: Hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) is an endosomal protein that participates in the trafficking and sorting of proteins to degradative or recycling pathways. HRS can bind ubiquitin directly and plays a key role in sorting ubiquitinated proteins to lysosomes. HRS has also been demonstrated to regulate protein sorting independent of its ubiquitin-binding motif.

Gene ID: 9146

NCBI Accession: NP_004703

UniProt: O14964

Pathways: CXCR4-mediated Signaling Events, EGFR Downregulation