IRAK1 antibody (AA 575-625)

Catalog No. ABIN7450369

This Rabbit Polyclonal antibody specifically detects IRAK1 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for IRAK1 antibody (AA 575-625) (ABIN7450369)

Target: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRAK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-IRAK1 Antibody

Binding Specificity: AA 575-625

Purpose: Rabbit anti-IRAK1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 575 and 625

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for IRAK1

Target: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Alternative Name: IRAK1

Background: Background: Interleukin-1 receptor-associated kinase 1 (IRAK1) is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B [taken from NCBI Entrez Gene (Gene ID: 3654)].

Gene ID: 3654

NCBI Accession: NP_001560

UniProt: P51617

Pathways: NF-kappaB Signaling, TLR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades