Stanniocalcin 2 antibody (AA 252-302)

Catalog No. ABIN7450781

The Rabbit Polyclonal anti-Stanniocalcin 2 antibody has been validated for WB and IP. It is suitable to detect Stanniocalcin 2 in samples from Human.

Quick Overview for Stanniocalcin 2 antibody (AA 252-302) (ABIN7450781)

Target: Stanniocalcin 2 (STC2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stanniocalcin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Stanniocalcin 2 Antibody

Binding Specificity: AA 252-302

Purpose: Rabbit anti-Stanniocalcin 2 Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Orangutan

Purification: Affinity Purified

Immunogen: between AA 252 and 302

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Stanniocalcin 2

Target: Stanniocalcin 2 (STC2)

Alternative Name: Stanniocalcin 2

Background: Background: Stanniocalcin 2 is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. Stanniocalcin 2 may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and is altered in some breast cancers [taken from NCBI Entrez Gene (GeneID: 8614)].

Gene ID: 8614

UniProt: O76061

Pathways: Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome