TBK1 antibody (C-Term)

Catalog No. ABIN7450810

This Rabbit Polyclonal antibody specifically detects TBK1 in WB and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for TBK1 antibody (C-Term) (ABIN7450810)

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-TBK1 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-TBK1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 675 and C-term

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TBK1

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Alternative Name: TBK1

Background: Background: TBK1 is a member of the I-kappa-B kinase (IKK) family that plays a role in embryonic development and in the innate immune response. In response to viral infection, TBK1 activity induces transcription of genes such as IFN-gamma inducible protein (ip10), and interferon beta (ifnb). TBK1 is also implicated in the NF-kappa-B activation pathway which involves phosphorylation of I-kappaB proteins and the release and translocation of the NF-kappa-B complex to the nucleus.

Gene ID: 29110

NCBI Accession: NP_037386

UniProt: Q9UHD2

Pathways: TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome