ThPok (AA 200-250) antibody

Catalog No. ABIN7450820

The Rabbit Polyclonal anti-ThPok antibody is suitable to detect ThPok in samples from Human. It has been validated for IP and WB.

Quick Overview for ThPok (AA 200-250) antibody (ABIN7450820)

Target: ThPok

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunoprecipitation (IP), Western Blotting (WB)

Product Details

Binding Specificity: AA 200-250

Purpose: Rabbit anti-ThPOK Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: Between AA 200 and 250

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details

Target: ThPok

Background: Background: ThPOK is a transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. ThPOK is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. [taken from the Universal Protein Resource (UniProt) O15156].

Gene ID: 51043

NCBI Accession: NP_056956

UniProt: O15156