MED13 antibody (AA 325-375)
Quick Overview for MED13 antibody (AA 325-375) (ABIN7450821)
Target
See all MED13 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 325-375
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Purpose
- Rabbit anti-THRAP1/TRAP240 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- between AA 325 and 375
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Isotype
- IgG
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Application Notes
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- MED13 (Mediator Complex Subunit 13 (MED13))
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Alternative Name
- THRAP1/TRAP240
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Background
- Background: THRAP/TRAP240 is a component of the TRAP (thyroid hormone receptor associated protein) complex. The TRAP complex is also known as Mediator and functions as a coactivator of transcription by bridging DNA bound transcription factors to the basal transcription machinery. THRAP1/TRAP240 has been reported to form a complex with MED12, cyclin C, and CDK8 and negatively regulates transcription.
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Gene ID
- 9969
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NCBI Accession
- NP_005112
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UniProt
- Q9UHV7
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha
Target
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