MED13 antibody (AA 325-375)

Catalog No. ABIN7450821

Product Details anti-MED13 Antibody

Target: MED13 (Mediator Complex Subunit 13 (MED13))

Binding Specificity: AA 325-375

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED13 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-THRAP1/TRAP240 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 325 and 375

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MED13

Target: MED13 (Mediator Complex Subunit 13 (MED13))

Alternative Name: THRAP1/TRAP240 (MED13 Products)

Background: Background: THRAP/TRAP240 is a component of the TRAP (thyroid hormone receptor associated protein) complex. The TRAP complex is also known as Mediator and functions as a coactivator of transcription by bridging DNA bound transcription factors to the basal transcription machinery. THRAP1/TRAP240 has been reported to form a complex with MED12, cyclin C, and CDK8 and negatively regulates transcription.

Gene ID: 9969

NCBI Accession: NP_005112

UniProt: Q9UHV7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha