MED13 antibody (AA 750-800)

Catalog No. ABIN7452097

Product Details anti-MED13 Antibody

Target: MED13 (Mediator Complex Subunit 13 (MED13))

Binding Specificity: AA 750-800

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED13 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-THRAP1/TRAP240 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 750 and 800

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MED13

Target: MED13 (Mediator Complex Subunit 13 (MED13))

Alternative Name: THRAP1/TRAP240 (MED13 Products)

Synonyms: ARC250 antibody, DRIP250 antibody, HSPC221 antibody, THRAP1 antibody, TRAP240 antibody, 1110067M05Rik antibody, D030023K18 antibody, Thrap1 antibody, Trap240 antibody, med13 antibody, wu:fb66c06 antibody, wu:fc43h07 antibody, wu:fc43h08 antibody, zgc:153454 antibody, skuld-like antibody, mediator complex subunit 13 antibody, mediator complex subunit 13b antibody, MED13 antibody, Med13 antibody, med13b antibody

Background: Background: THRAP/TRAP240 is a component of the TRAP (thyroid hormone receptor associated protein) complex. The TRAP complex is also known as Mediator and functions as a coactivator of transcription by bridging DNA bound transcription factors to the basal transcription machinery. THRAP1/TRAP240 has been reported to form a complex with MED12, cyclin C, and CDK8 and negatively regulates transcription.

Gene ID: 9969

NCBI Accession: NP_005112

UniProt: Q9UHV7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha