PURB antibody (AA 262-312)

Catalog No. ABIN7451054

The Rabbit Polyclonal anti-PURB antibody has been validated for IP. It is suitable to detect PURB in samples from Human.

Quick Overview for PURB antibody (AA 262-312) (ABIN7451054)

Target: PURB (Purine-Rich Element Binding Protein B (PURB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PURB antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-PURB Antibody

Binding Specificity: AA 262-312

Purpose: Rabbit anti-Pur-beta Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat

Purification: Affinity Purified

Immunogen: Between AA 262 and 312

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451054 has not performed satisfactorily when used for WB of Pur-beta in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Pur-beta.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PURB

Target: PURB (Purine-Rich Element Binding Protein B (PURB))

Alternative Name: Pur-beta

Background: Background: Pur-beta (purine-rich element binding protein B) is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of the Pur-beta gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia [taken from NCBI Entrez Gene (Gene ID: 5814)].

Gene ID: 5814

NCBI Accession: NP_150093

UniProt: Q96QR8