PURB antibody (AA 1-50)
Quick Overview for PURB antibody (AA 1-50) (ABIN7451499)
Target
See all PURB AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-50
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Purpose
- Rabbit anti-Pur-beta Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- Between AA 1 and 50
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Isotype
- IgG
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Application Notes
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IP: 2 - 10 μg/mg lysate
WB: Not recommended
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- PURB (Purine-Rich Element Binding Protein B (PURB))
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Alternative Name
- Pur-beta
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Background
- Background: Pur-beta (purine-rich element binding protein B) is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of the Pur-beta gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia [taken from NCBI Entrez Gene (Gene ID: 5814)].
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Gene ID
- 5814
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NCBI Accession
- NP_150093
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UniProt
- Q96QR8
Target
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