PPP1R12A antibody (AA 400-450)

Catalog No. ABIN7451591

The Rabbit Polyclonal anti-PPP1R12A antibody has been validated for WB and IP. It is suitable to detect PPP1R12A in samples from Human.

Quick Overview for PPP1R12A antibody (AA 400-450) (ABIN7451591)

Target: PPP1R12A (Myosin Phosphatase, Target Subunit 1 (PPP1R12A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R12A antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-PPP1R12A Antibody

Binding Specificity: AA 400-450

Purpose: Rabbit anti-MYPT1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 400 and 450

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PPP1R12A

Target: PPP1R12A (Myosin Phosphatase, Target Subunit 1 (PPP1R12A))

Alternative Name: MYPT1

Background: Background: MYPT1 is the non-catalytic regulatory subunit of the myosin phosphatase (MP). MYPT1 is the smooth-muscle/platelet isoform. MYPT1 is a substrate of and is regulated by Rho-protein kinase. Phosphorylation of MYPT1 by Rho kinase inhibits MP activity.

Gene ID: 4659

NCBI Accession: NP_002471

UniProt: O14974

Pathways: M Phase