ARFGAP1 antibody (AA 356-406)
Quick Overview for ARFGAP1 antibody (AA 356-406) (ABIN7451637)
Target
See all ARFGAP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 356-406
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Purpose
- Rabbit anti-ArfGAP1 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- between AA 356 and 406
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Isotype
- IgG
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Application Notes
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))
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Alternative Name
- ArfGAP1
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Background
- Background: ADP-ribosylation factor GTPase activating protein 1 (ArfGAP1) is a GTPase activating protein that interacts with the GTPase ADP-ribosylation factor (Arf) in Golgi membranes and vesicles. ArfGAP1 promotes the hydrolysis of ARF1-bound GTP to promote fusion of golgi-derived vesicles with the target compartment. Although they are differentially regulated, ArfGAP1, ArfGAP2, and ArfGAP3 have been shown to play overlapping roles in COPI-mediated transport and in the maintenance of Golgi organization.
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Gene ID
- 55738
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NCBI Accession
- NP_060679
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UniProt
- Q8N6T3
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Pathways
- p53 Signaling, ER-Nucleus Signaling, Unfolded Protein Response
Target
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