CPSF4 antibody (AA 245-269)

Catalog No. ABIN7451717

The Rabbit Polyclonal anti-CPSF4 antibody is suitable to detect CPSF4 in samples from Human and Mouse. It has been validated for WB and IP.

Quick Overview for CPSF4 antibody (AA 245-269) (ABIN7451717)

Target: CPSF4 (Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPSF4 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-CPSF4 Antibody

Binding Specificity: AA 245-269

Purpose: Rabbit anti-CPSF30 Antibody, Affinity Purified

Predicted Reactivity: Rat,X. laevis,X. tropicalis,Bovine

Purification: Affinity Purified

Immunogen: between AA 245 and 269

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CPSF4

Target: CPSF4 (Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4))

Alternative Name: CPSF30

Background: Background: CPSF30/CPSF4 (cleavage and polyadenylation specific factor 4, 30 kDa subunit) is a subunit of the cleavage and polyadenylation specificity factor (CPSF) involved in mammalian mRNA 3'-end processing. CPSF, along with CstF (cleavage and stimulation factor), is critical for the recognition of cis-acting sequence elements on the pre-mRNA that dictate the site of cleavage and subsequent polyadenylation. CPSF exists as a complex of four proteins that includes CPSF160/CPSF1, CPSF100/CPSF2, CPSF73/CPSF3, and CPSF30/CPSF4. Studies of the Arabidopsis CPSF30/CPSF4 ortholog have revealed that CPSF30/CPSF4 may function as a processing endonuclease and interacts with Fip1, an integral subunit of CPSF.

Gene ID: 10898

NCBI Accession: NP_006684

UniProt: O95639