KDM3A antibody (AA 1271-1321)

Catalog No. ABIN7451824

This Rabbit Polyclonal antibody specifically detects KDM3A in WB and IP. It exhibits reactivity toward Human.

Quick Overview for KDM3A antibody (AA 1271-1321) (ABIN7451824)

Target: KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM3A antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-KDM3A Antibody

Binding Specificity: AA 1271-1321

Purpose: Rabbit anti-JMJD1A/JHDM2A Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1271 and 1321

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for KDM3A

Target: KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

Alternative Name: JMJD1A/JHDM2A

Background: Background: JMJD1A/JHDM2A is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in the regulation of chromatin dynamics and influences transcriptional activation and suppression. JMJD1A/JHDM2A specifically demethylates mono- and dimethyl-histone 3 lysine 9. Demethylation of histones by JMJD1A has been shown to facilitate transcriptional activation by the androgen receptor and promote transcription of smooth muscle cell differentiation marker.

Gene ID: 55818

NCBI Accession: NP_060903

UniProt: Q9Y4C1

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Warburg Effect