MCL-1 antibody (AA 75-125)

Catalog No. ABIN7451866

This Rabbit Polyclonal antibody specifically detects MCL-1 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for MCL-1 antibody (AA 75-125) (ABIN7451866)

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCL-1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-MCL-1 Antibody

Binding Specificity: AA 75-125

Purpose: Rabbit anti-MCL1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 75 and 125

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MCL-1

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Alternative Name: MCL1

Background: Background: Myeloid cell leukemia sequence 1 (MCL1) is involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. MCL1 mediates its effects by interactions with a number of other regulators of apoptosis. Two transcripts from the MCL1 gene have been identified. Isoform 1 enhances cell survival, while isoforms 2 promotes apoptosis.

Gene ID: 4170

NCBI Accession: NP_068779

UniProt: Q07820

Pathways: MAPK Signaling