IVNS1ABP antibody (AA 50-100)

Catalog No. ABIN7451899

This Rabbit Polyclonal antibody specifically detects IVNS1ABP in WB and IP. It exhibits reactivity toward Human.

Quick Overview for IVNS1ABP antibody (AA 50-100) (ABIN7451899)

Target: IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IVNS1ABP antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-IVNS1ABP Antibody

Binding Specificity: AA 50-100

Purpose: Rabbit anti-NS1-BP Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 50 and 100

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for IVNS1ABP

Target: IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

Alternative Name: NS1-BP

Target Type: Influenza Protein

Background: Background: NS1-binding protein (NS1-BP) plays a role in cell division and in the dynamic organization of the actin skeleton by functioning as a stabilizer of actin filaments via its association with F-actin through Kelch repeats. NS1-BP may be a component of the cellular splicing machinery with a role in pre-mRNA splicing and may mediate the inhibition of splicing by NS/influenza virus NS1A protein. NS1-BP has also been found to function as modifier of the AHR/Aryl hydrocarbon receptor pathway by increasing the concentration of AHR available to activate transcription [taken from the Universal Protein Resource (UniProt) Q9Y6YO].

Gene ID: 10625

NCBI Accession: NP_006460

UniProt: Q9Y6Y0

Pathways: Negative Regulation of intrinsic apoptotic Signaling