NUP98 antibody (AA 600-650)

Catalog No. ABIN7451911

This Rabbit Polyclonal antibody specifically detects NUP98 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for NUP98 antibody (AA 600-650) (ABIN7451911)

Target: NUP98 (Nucleoporin 98kDa (NUP98))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP98 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-NUP98 Antibody

Binding Specificity: AA 600-650

Purpose: Rabbit anti-NUP98 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 600 and 650

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for NUP98

Target: NUP98 (Nucleoporin 98kDa (NUP98))

Alternative Name: NUP98

Background: Background: The nuclear pore complex (NPC) is a structure that spans the nuclear envelope and provides a conduit between the nucleus and cytoplasm for the nucleocytoplasmic transport of macromolecules. The main components of the NPC are nucleoporins. There are about 30 different human Nups that have been identified. Nup98 is a 98 kDa protein generated from a 186 kDa precursor. The proteolytic cleavage of the 186 kDa precursor also results in a 96 kDa nucleoporin, Nup96. Nup98 and Nup96 have been shown to interact with each other and both play a role in bidirectional transport across the NPC. The NUP98 gene localizes to tumor-suppressor region associated with several types of cancer.

Gene ID: 4928

NCBI Accession: NP_057404

UniProt: P52948

Pathways: Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome