MAPK14 antibody (AA 1-50)

Catalog No. ABIN7451921

The Rabbit Polyclonal anti-MAPK14 antibody is suitable to detect MAPK14 in samples from Human and Mouse. It has been validated for WB and IP.

Quick Overview for MAPK14 antibody (AA 1-50) (ABIN7451921)

Target: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK14 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-MAPK14 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-p38 MAPK Antibody, Affinity Purified

Predicted Reactivity: Rat,Dog,Chimpanzee

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MAPK14

Target: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Alternative Name: p38 MAPK

Background: Background: p38 MAPK is a member of the MAP (mitogen-activated protein) kinase family that is involved in cellular signaling for a wide variety of activities which includes proliferation, differentiation, and transcriptional regulation. p38 MAPK is responsive to growth factors as well as a variety of cellular stress signals such as UV light, inflammatory cytokines, and osmotic shock. Substrates of P38 MAPK include ATF2, MEF2C, MAX, CDC25B and p53. p38 MAPK is activated by MAP kinase kinases such as MAP2K3, MAP2K6, and MAP2K4.

Gene ID: 1432

NCBI Accession: NP_001306

UniProt: Q16539

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins