XPC antibody (AA 890-940)

Catalog No. ABIN7452171

This anti-XPC antibody is a Rabbit Polyclonal antibody detecting XPC in WB and IP. Suitable for Human.

Quick Overview for XPC antibody (AA 890-940) (ABIN7452171)

Target: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XPC antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-XPC Antibody

Binding Specificity: AA 890-940

Purpose: Rabbit anti-XPC Antibody, Affinity Purified

Predicted Reactivity: Dog,Orangutan,Monkey,Gorilla,Chimpanzee

Purification: Affinity Purified

Immunogen: between AA 890 and 940

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for XPC

Target: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Alternative Name: XPC

Background: Background: Defects in XPC are a cause of xeroderma pigmentosum complementation group C, a rare autosomal recessive diseased characterized by hypersensitivity to sunlight and an elevated risk of skin cancer on sun-exposed areas. XPC is involved in nucleotide excision repair and performs its function as part of a heterodimeric complex with HHR23B. XPC has been found to play a role in the early stages of repair that involve incising damaged DNA.

Gene ID: 7508

NCBI Accession: NP_004619

UniProt: Q01831

Pathways: p53 Signaling, DNA Damage Repair