CSTF2T antibody (AA 225-275)
Quick Overview for CSTF2T antibody (AA 225-275) (ABIN7452301)
Target
See all CSTF2T AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 225-275
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Purpose
- Rabbit anti-CSTF2T/TauCSTF64 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- between AA 225 and 275
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Isotype
- IgG
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anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (N-Term) antibody
CSTF2T Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (AA 1-616) antibodyCSTF2T Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (AA 420-560) antibodyCSTF2T Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) antibodyCSTF2T Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (AA 566-616) antibodyCSTF2T Reactivity: Human IHC Host: Rabbit Polyclonal unconjugated
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (AA 460-509) antibodyCSTF2T Reactivity: Human, Horse, Dog, Cow, Pig WB Host: Rabbit Polyclonal unconjugated
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (AA 521-570) antibodyCSTF2T Reactivity: Human, Rat, Horse, Cow, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (Internal Region) antibodyCSTF2T Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (AA 566-616) antibodyCSTF2T Reactivity: Human WB, IP, IHC (fp) Host: Rabbit Polyclonal unconjugated
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) (C-Term) antibodyCSTF2T Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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Application Notes
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-CSTF2T/TauCSTF64 antibody A301-487A.
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- CSTF2T (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T))
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Alternative Name
- CSTF2T/TauCSTF64
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Background
- Background: CSTF2T, also known as tauCSTF-64, is a paralog of CstF-64, a component of the cleavage stimulation factor (CstF) that processes 3'-end formation and polyadenylation of mRNAs. The human CSTF2T/TauCSTF64 gene is located at 10q22-23, a site associated with neurological problems and male infertility. CSTF2T is expressed in all tissues and throughout meiosis in male germ cells. CstF-64 is also expressed ubiquitously, however because it is located on the X chromosome, its expression is temporarily silenced in germ cells by meiotic sex chromosome inactivation. During this inactivation, it is hypothesized that CSTF2T/TauCSTF64 can compensate for the loss of CstfF-64 expression. Recently, targeted disruption of CSTF2T/TauCSTF64 in mice has been shown to cause aberrant spermatogenesis and infertility providing more evidence for its importance in spermatogenesis.
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Gene ID
- 23283
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NCBI Accession
- NP_056050
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UniProt
- Q9H0L4
Target
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