DOT1L antibody (C-Term)

Catalog No. ABIN7452312

The Rabbit Polyclonal anti-DOT1L antibody (ABIN7452312) specifically detects DOT1L in IP. The antibody is reactive with Human samples.

Quick Overview for DOT1L antibody (C-Term) (ABIN7452312)

Target: DOT1L (DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOT1L antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-DOT1L Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-DOT1L Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Orangutan

Purification: Affinity Purified

Immunogen: between AA 1485 and C-term

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-DOT1L antibody A300-953A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DOT1L

Target: DOT1L (DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L))

Alternative Name: DOT1L

Background: Background: DOT1L is a histone methyltransferase that methylates nucleosomal histone H3 on lysine 79. In contrast to other lysine histone methyltransferase, DOT1L does not contain a SET domain, a domain shown to be necessary for methyltransferase activity.

Gene ID: 84444

NCBI Accession: NP_115871

UniProt: Q8TEK3