POLM antibody (AA 640-690)

Catalog No. ABIN7452397

This Rabbit Polyclonal antibody specifically detects POLM in IP. It exhibits reactivity toward Human.

Quick Overview for POLM antibody (AA 640-690) (ABIN7452397)

Target: POLM (Polymerase (DNA Directed), mu (POLM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLM antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-POLM Antibody

Binding Specificity: AA 640-690

Purpose: Rabbit anti-Pol Iota Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 640 and 690

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-Pol Iota antibody ABIN7451969.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for POLM

Target: POLM (Polymerase (DNA Directed), mu (POLM))

Alternative Name: Pol Iota

Background: Background: Pol Iota is a DNA polymerase involved in DNA repair and translesion DNA synthesis. Pol Iota is a member of the Rad30 family of DNA polymerases which exhibit low fidelity when replicating undamaged DNA, and in this context may play a role in the hypermutation of immunoglobulin genes. Pol Iota is also known as RAD30B and is a paralog of RAD30A, also known as Pol eta.

Gene ID: 11201

NCBI Accession: NP_009126

UniProt: Q9UNA4

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response