NCOR2 antibody (AA 1925-1975)

Catalog No. ABIN7452437

The Rabbit Polyclonal anti-NCOR2 antibody has been validated for IP. It is suitable to detect NCOR2 in samples from Human.

Quick Overview for NCOR2 antibody (AA 1925-1975) (ABIN7452437)

Target: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOR2 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-NCOR2 Antibody

Binding Specificity: AA 1925-1975

Purpose: Rabbit anti-SMRT Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1925 and 1975

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-SMRT antibody ABIN7452053.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for NCOR2

Target: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Alternative Name: SMRT

Background: Background: SMRT (silencing mediator of retinoid and thyroid hormone receptor) mediates gene repression by interacting with nuclear receptors such as the thyroid hormone receptor, retinoic acid receptor, progesterone receptor, androgen receptor, estrogen receptor, and glucocorticoids receptor. SMRT mediates repression by associating with SIN3A/B and the histone deacetylases, HDAC1 and HDAC2, and promoting the formation of repressive chromatin structures.

Gene ID: 9612

UniProt: Q9Y618

Pathways: Notch Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha