HYOU1 antibody (AA 949-999)

Catalog No. ABIN7452655

This Rabbit Polyclonal antibody specifically detects HYOU1 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for HYOU1 antibody (AA 949-999) (ABIN7452655)

Target: HYOU1 (Hypoxia Up Regulated 1 (HYOU1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HYOU1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-HYOU1 Antibody

Binding Specificity: AA 949-999

Purpose: Rabbit anti-ORP150/HYOU1 Antibody, Affinity Purified

Predicted Reactivity: Rat

Purification: Affinity Purified

Immunogen: between AA 949 and 999

Isotype: IgG

Application Details

Application Notes:

IP: 20-40 μL/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for HYOU1

Target: HYOU1 (Hypoxia Up Regulated 1 (HYOU1))

Alternative Name: ORP150/HYOU1

Background: Background: ORP150 belongs to the heat shock protein 70 family that is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. ORP150 is also thought to play an important role in protein folding and secretion in the ER and is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. Finally, ORP150 has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. [taken from NCBI Entrez Gene (Gene ID: 10525)].

Gene ID: 10525

UniProt: Q9Y4L1

Pathways: ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome