AXL antibody (AA 844-894)

Catalog No. ABIN7452749

The Rabbit Polyclonal anti-AXL antibody has been validated for WB and IP. It is suitable to detect AXL in samples from Human.

Quick Overview for AXL antibody (AA 844-894) (ABIN7452749)

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AXL antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-AXL Antibody

Binding Specificity: AA 844-894

Purpose: Rabbit anti-AXL Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 844 and 894

Isotype: IgG

Application Details

Application Notes:

IP: 5 - 15 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for AXL

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Alternative Name: AXL

Background: Background: AXL is a receptor tyrosine kinase (RTK) that binds the ligand Gas6 (growth-arrest specific gene). It is part of a sub-family of RTKs that includes AXL, SKY and MER. The AXL gene was first identified as a transforming cDNA isolated from patients with chronic myelogenous leukemia. AXL-Gas6 signaling is implicated in cellular responses such as cell survival, proliferation, migration, and adhesion, and it may be involved in cancer progression.

Gene ID: 558

NCBI Accession: NP_068713

UniProt: P30530

Pathways: RTK Signaling, Cellular Response to Molecule of Bacterial Origin