FANCM antibody (AA 1-50)

Catalog No. ABIN7452758

The Rabbit Polyclonal anti-FANCM antibody has been validated for WB and IP. It is suitable to detect FANCM in samples from Human.

Quick Overview for FANCM antibody (AA 1-50) (ABIN7452758)

Target: FANCM (Fanconi Anemia Complementation Group M (FANCM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCM antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-FANCM Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-FANCM Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 5 - 15 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FANCM

Target: FANCM (Fanconi Anemia Complementation Group M (FANCM))

Alternative Name: FANCM

Background: Background: FANCM (Fanconi anemia, complementation group M) is a protein involved in DNA repair. Defects in FANCM are the cause of Fanconi anemia, a heterogenous autosomal recessive disorder characterized by congenital malformations and a predisposition to cancer. The FANCM gene is one of 13 complementation groups that include FANCA, FANCB, FANCC, FANCD1/BRCA2, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ/BRIP1, FANCL, FANCM, and FANCN/PALB2. The FANC members are not homologous proteins but are related by their assembly into a common nuclear complex.

Gene ID: 57697

NCBI Accession: NP_065988

UniProt: Q8IYD8

Pathways: DNA Damage Repair