RLTPR antibody (AA 1385-1435)
Quick Overview for RLTPR antibody (AA 1385-1435) (ABIN7452808)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1385-1435
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Purpose
- Rabbit anti-CARMIL2 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- between AA 1385 and 1435
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Isotype
- IgG
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Application Notes
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IP: 50-100 μL/mg lysate
WB: 1:10,000 - 1:25,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- RLTPR (RGD Motif, Leucine Rich Repeats, Tropomodulin Domain and Proline-Rich Containing (RLTPR))
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Alternative Name
- CARMIL2
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Background
- Background: Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization. Plays a role in cell protrusion formations, involved in cell polarity, lamellipodial assembly, membrane ruffling and macropinosome formations. Involved as well in cell migration and invadopodia formation during wound healing. [taken from the Universal Protein Resource (UniProt) Q6F5E8].
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Gene ID
- 146206
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UniProt
- Q6F5E8
Target
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