JUP antibody (AA 1-50)

Catalog No. ABIN7453165

This Rabbit Polyclonal antibody specifically detects JUP in WB. It exhibits reactivity toward Human.

Quick Overview for JUP antibody (AA 1-50) (ABIN7453165)

Target: JUP (Junction Plakoglobin (JUP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JUP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-JUP Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-Plakoglobin Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for JUP

Target: JUP (Junction Plakoglobin (JUP))

Alternative Name: Plakoglobin

Background: Background: Plakoglobin (gamma-catenin) is a member of the catenin family of proteins. It bears an armadillo repeat motif and plays a role in cell signaling, but unlike beta-catenenin, which plays a major role in the Wnt signaling pathway, plakoglobin is thought to act as a tumor/metastasis suppressor. Plakoglobin also functions as a junctional plaque protein and forms complexes with cadherins and desmosomal cadherins.

Gene ID: 3728

NCBI Accession: NP_002221

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location