Recombinant PDGFRA antibody (AA 24-525)

Catalog No. ABIN7453341

The Rabbit Monoclonal anti-PDGFRA antibody (Clone BLR078G) (ABIN7453341) specifically detects PDGFRA in WB, ICC and IP. The antibody is reactive with Human samples.

Quick Overview for Recombinant PDGFRA antibody (AA 24-525) (ABIN7453341)

Target: PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PDGFRA antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: BLR078G

Product Details anti-PDGFRA Antibody

Binding Specificity: AA 24-525

Purpose: Rabbit anti-PDGFR alpha Recombinant Monoclonal Antibody [BLR078G]

Purification: Purified

Immunogen: residues 24-525 (ECD)

Isotype: IgG

Application Details

Application Notes:

IP: 20 μL/1 mg lysate

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 17:40:00

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 250 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for PDGFRA

Target: PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

Alternative Name: PDGFR alpha

Background: Platelet derived growth factor receptor alpha is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both PDGFR alpha and beta polypeptides. PDGFR alpha plays a role in organ development, wound healing, and tumor progression [taken from NCBI Entrez Gene (Gene ID: 5156)].

Gene ID: 5156

UniProt: P16234

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling