Recombinant AXL antibody (AA 33-440)

Catalog No. ABIN7453376

The Rabbit Monoclonal anti-AXL antibody has been validated for WB, FACS, IP and ICC. It is suitable to detect AXL in samples from Human and Mouse.

Quick Overview for Recombinant AXL antibody (AA 33-440) (ABIN7453376)

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This AXL antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: BLR222K

Product Details anti-AXL Antibody

Binding Specificity: AA 33-440

Purpose: Rabbit anti-AXL Recombinant Monoclonal Antibody [BLR222K]

Immunogen: residues 33-440(ECD)

Isotype: IgG

Application Details

Application Notes:

IP: 6 μL/1 mg lysate

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 01:01,00

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for AXL

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Alternative Name: AXL

Background: Background: AXL is a receptor tyrosine kinase (RTK) that binds the ligand Gas6 (growth-arrest specific gene). It is part of a sub-family of RTKs that includes AXL, SKY and MER. The AXL gene was first identified as a transforming cDNA isolated from patients with chronic myelogenous leukemia. AXL-Gas6 signaling is implicated in cellular responses such as cell survival, proliferation, migration, and adhesion, and it may be involved in cancer progression.

Gene ID: 558

NCBI Accession: NP_068713

UniProt: P30530

Pathways: RTK Signaling, Cellular Response to Molecule of Bacterial Origin