TCEB2 antibody (AA 68-118)

Catalog No. ABIN7453458

The Rabbit Polyclonal anti-TCEB2 antibody (ABIN7453458) specifically detects TCEB2 in WB, IP and IHC (fp). The antibody is reactive with Human and Mouse samples.

Quick Overview for TCEB2 antibody (AA 68-118) (ABIN7453458)

Target: TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCEB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-TCEB2 Antibody

Binding Specificity: AA 68-118

Purpose: Rabbit anti-TCEB2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 68 and 118

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:500 - 1:2,500

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TCEB2

Target: TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))

Alternative Name: TCEB2

Background: Background: TCEB2, also known as Elongin B, is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation [taken from NCBI Entrez Gene (Gene ID: 6923)].

Gene ID: 6923

NCBI Accession: NP_009039

UniProt: Q15370

Pathways: SARS-CoV-2 Protein Interactome