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Cullin 2 antibody (AA 150-200)

The Rabbit Polyclonal anti-Cullin 2 antibody has been validated for WB, IP and IHC (fp). It is suitable to detect Cullin 2 in samples from Human.
Catalog No. ABIN7453499

Quick Overview for Cullin 2 antibody (AA 150-200) (ABIN7453499)

Target

See all Cullin 2 (CUL2) Antibodies
Cullin 2 (CUL2)

Reactivity

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  • 26
  • 7
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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Cullin 2 antibody is un-conjugated

Application

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • Binding Specificity

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    AA 150-200

    Purpose

    Rabbit anti-Cul2 Antibody, Affinity Purified

    Predicted Reactivity

    Mouse,Orangutan

    Purification

    Affinity Purified

    Immunogen

    between AA 150 and 200

    Isotype

    IgG
  • Application Notes

    IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: Not recommended. Use rabbit anti-Cul2 antibody ABIN7451725.

    Restrictions

    For Research Use only
  • Concentration

    1000 μg/mL

    Buffer

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Expiry Date

    12 months
  • Target

    Cullin 2 (CUL2)

    Alternative Name

    Cul2

    Background

    Background: Cullin-2 (Cul2) is a core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. Cul2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme [taken from the Universal Protein Resource (UniProt) Q13617].

    Gene ID

    8453

    NCBI Accession

    NP_003582

    UniProt

    Q13617

    Pathways

    M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome
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