CPSF3L antibody (AA 550-600)

Catalog No. ABIN7453583

Product Details anti-CPSF3L Antibody

Target: CPSF3L (Cleavage and Polyadenylation Specific Factor 3-Like (CPSF3L))

Binding Specificity: AA 550-600

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPSF3L antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-INT11 Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: between AA 550 and 600

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CPSF3L

Target: CPSF3L (Cleavage and Polyadenylation Specific Factor 3-Like (CPSF3L))

Alternative Name: INT11 (CPSF3L Products)

Background: Background: INT11 has been identified as a component of the twelve-subunit integrator complex that functions in RNA Pol II mediated 3'-end mRNA processing of the U1 and U2 small nuclear RNAs (snRNAs). INT11 is a beta-lactamase family member that has sequence similarity to the cleavage and polyadenylation specificity factors CPSF-73 and CPSF-100.

Gene ID: 54973

NCBI Accession: NP_060341

UniProt: Q5TA45