IQGAP1 antibody (AA 1-50)

Catalog No. ABIN7453634

The Rabbit Polyclonal anti-IQGAP1 antibody is suitable to detect IQGAP1 in samples from Human. It has been validated for WB, IP and IHC (fp).

Quick Overview for IQGAP1 antibody (AA 1-50) (ABIN7453634)

Target: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IQGAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-IQGAP1 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-IQGAP1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for IQGAP1

Target: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Alternative Name: IQGAP1

Background: Background: IQGAP1 (IQ motif containing GTPase activating protein 1) interacts with the Rho-family GTPases, CDC42 and RAC1. It has been shown to localize to sites of cell-cell contact and regulate cadherin-mediated cell-cell adhesion. In addition to its role in cell adhesion, it is also involved in cell polarization and migration.

Gene ID: 8826

NCBI Accession: NP_003861

UniProt: P46940

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2