MBD4 antibody (AA 1-50)

Catalog No. ABIN7453727

Product Details anti-MBD4 Antibody

Target: MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))

Binding Specificity: AA 1-50

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBD4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP)

Purpose: Rabbit anti-MBD4 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MBD4

Target: MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))

Alternative Name: MBD4 (MBD4 Products)

Synonyms: MED1 antibody, Med1 antibody, methyl-CpG binding domain 4, DNA glycosylase antibody, methyl-CpG binding domain protein 4 antibody, methyl-CpG binding domain 4 DNA glycosylase antibody, MBD4 antibody, Mbd4 antibody

Background: Background: MBD4 (methyl-CpG-binding domain protein 4) is a member of the MBD family of proteins that mainly functions to bind methylated CpG sites and to repress gene transcription. Unlike its family members, MBD4 exhibits thymine glycosylase activity and has been shown to play an important role in DNA mismatch repair and apoptosis.

Gene ID: 8930

NCBI Accession: NP_003916

UniProt: O95243

Pathways: DNA Damage Repair